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US Pharma Companies

Peer Benchmarking Tearsheet (H1'2023)

As the pharmaceutical industry adapts to a post-pandemic landscape, we are analyzing the mid-year performance of the top ten US companies.

Sales metrics present a diverse landscape, with the majority of companies experiencing modest growth at best. Pfizer recorded a significant 41.9% year-over-year decline as global demand for its COVID-19 offerings diminished. AbbVie and Bristol Myers Squibb also reported decreased year-over-year sales by 7.2% and 4.1%, respectively. The expiration of Humira's patent exclusivity has negatively impacted AbbVie, while lower Revlimid sales have affected Bristol Myers Squibb's performance. On the other hand, Vertex maintained strong growth driven by its cystic fibrosis product line; Eli Lilly benefited from surging diabetes drug sales; and Regeneron's collaboration with Sanofi and robust Libtayo sales boosted its growth.

Increasing research and development (R&D) and marketing costs have surpassed revenue growth across all the companies, influencing year-over-year growth in operating profits. However, profit margins have remained consistent.

(Values in US$ Billion, reported numbers for H1' 2023 unless specified)
JNJ LLY MRK ABBV PFE BMY AMGN GILD REGN VRTX
                   
Sales 50.28 15.27 29.52 26.09 31.02 22.56 13.09 12.95 6.32 4.87
yoy 6.0% 6.8% -3.2% -7.2% -41.9% -4.1% 2.0% 0.8% 8.6% 13.4%
Sales [2023 est.] 100.23 33.65 59.27 53.45 66.01 44.95 27.08 26.86 12.77 9.87
Sales [2022] 94.94 28.54 59.28 58.05 100.33 46.16 26.32 27.28 12.17 8.93
yoy 5.6% 17.9% 0.0% -7.9% -34.2% -2.6% 2.9% -1.5% 4.9% 10.5%
                   
Gross Profit 33.67 11.84 21.57 17.86 22.89 17.12 9.56 10.11 5.46 4.29
yoy 5.4% 9.7% 3.2% -10.2% -34.2% -6.7% -2.1% 1.2% 6.6% 13.4%
margin 67.0% 77.5% 73.1% 68.5% 73.8% 75.9% 73.0% 78.0% 86.4% 88.2%
                   
RnD* 7.39 4.34 17.60 4.03 5.15 4.58 2.17 2.85 2.19 1.53
yoy 3.2% 28.0% 227.4% 29.6% 0.7% 0.0% 8.7% 25.2% 33.5% 27.2%
% of sales 14.7% 28.4% 59.6% 15.4% 16.6% 20.3% 16.6% 22.0% 34.6% 31.4%
                   
SGnA 12.80 3.67 5.18 6.31 6.91 3.70 2.55 3.17 1.25 0.50
yoy 5.3% 15.4% 7.2% -26.1% 22.5% 2.2% -0.1% 29.8% 35.3% 17.0%
% of sales 25.5% 24.1% 17.6% 24.2% 22.3% 16.4% 19.5% 24.5% 19.8% 10.3%
                   
Operating Income 13.20 3.82 -1.43 7.28 10.77 8.85 4.61 3.37 1.96 1.81
yoy 6.1% -9.4% -113.6% -9.1% -54.5% -12.8% -1.5% 51.4% -17.1% -15.9%
margin 26.3% 25.0% -4.8% 27.9% 34.7% 39.2% 35.2% 26.0% 31.1% 37.1%
                   
Net Income 5.08 3.11 -3.15 2.27 7.89 4.34 4.22 2.02 1.79 1.62
yoy -49.1% 8.8% -138.1% -58.2% -55.6% 60.2% 51.1% 76.5% -2.2% 2.7%
margin 10.1% 20.4% -10.7% 8.7% 25.5% 19.3% 32.2% 15.6% 28.3% 33.2%
                   
Adj. Net Income** 14.43 3.37 -1.65 9.56 10.88 8.00 4.82 3.41 2.35 1.81
yoy 2.7% -3.9% -116.2% -17.9% -48.2% -4.8% -0.3% -26.8% -3.9% -1.6%
margin 28.7% 22.1% -5.6% 36.6% 35.1% 35.4% 36.8% 26.4% 37.2% 37.1%
% diff vs GAAP 184.2% 8.4% -47.6% 321.5% 37.8% 84.1% 14.3% 68.7% 31.5% 11.9%
                   
Op. Cash Flows 7.44 2.36 5.04 10.51 0.00 4.86 5.17 4.08 2.39 2.03
yoy -22.2% -36.3% -44.4% 6.0% -100.0% -20.0% 26.4% 12.1% -10.4% -2.9%
% of sales 14.8% 15.5% 17.1% 40.3% 0.0% 21.5% 39.5% 31.5% 37.8% 41.8%
                   
Capital Expenditure 1.99 1.41 1.97 0.35 2.05 0.54 0.62 0.25 0.29 0.10
yoy 35.2% 91.0% -6.7% 15.7% 47.3% 2.3% 41.1% -36.4% -1.4% -13.0%
% of sales 4.0% 9.2% 6.7% 1.4% 6.6% 2.4% 4.7% 1.9% 4.6% 2.1%
                   
Free Cash Flows 5.45 0.96 3.07 10.16 -2.05 4.32 4.56 3.83 2.10 1.93
% of sales 10.8% 6.3% 10.4% 38.9% -6.6% 19.1% 34.8% 29.6% 33.2% 39.7%
                   
Cash & ST Inv. 28.51 2.83 6.38 8.77 44.79 8.73 34.25 0.96 8.93 11.24
yoy -12.5% 3.4% -37.0% -12.0% 34.5% -34.0% 376.8% 4.2% 18.0% 21.4%
                   
Total Debt 45.60 18.82 36.91 61.02 65.34 37.68 61.54 25.25 1.98 4.88
yoy 39.9% 11.9% 16.6% -16.3% 62.2% -10.4% 68.5% -3.7% 0.1% 33.7%
net debt 17.10 15.99 30.53 52.25 20.56 28.95 27.30 24.28 -6.95 -6.36
total debt to equity 0.60 1.69 0.95 4.74 0.66 1.18 9.08 1.20 0.08 0.32
                   
Assets 191.69 54.81 104.47 135.37 220.17 93.49 90.27 62.34 30.66 20.35
debt to assets 0.24 0.34 0.35 0.45 0.30 0.40 0.68 0.40 0.06 0.00
return on assets [ltm] 6.8% 11.9% 3.0% 6.4% 9.8% 8.5% 8.8% 8.7% 14.0% 16.5%
return on equity [ltm] 17.1% 58.3% 8.0% 67.6% 21.7% 24.9% 117.7% 25.8% 17.9% 21.8%
asset turnover 0.52 0.61 0.57 0.39 0.30 0.48 0.30 0.43 0.42 0.49
                   
Share Price (08/23/23) 164.53 553.36 111.3 147.08 36.66 61.56 257.36 77.04 840.81 350.6
52w high 179.8 553.7 117.6 165.2 52.8 79.1 283.3 86.9 844.4 362.5
52w low 149.9 255.4 73.6 129.0 35.0 60.2 212.6 54.3 548.3 235.0
                   
EPS, Diluted 1.93 3.44 -1.24 1.26 1.38 2.06 7.86 1.63 15.68 6.21
year ago 3.73 3.16 3.25 3.03 3.10 1.25 5.13 0.92 16.07 6.09
Adj. EPS, Diluted 5.48 3.73 -0.65 5.37 1.90 3.80 8.98 2.71 20.32 6.95
year ago 5.26 3.87 4.01 6.52 3.66 3.89 8.89 3.70 21.26 7.11
EPS Estimate [2023] 10.75 9.85 3.02 11.06 3.30 7.43 18.25 6.63 41.79 14.71
year ago 10.15 7.94 7.48 13.77 6.58 7.70 17.69 7.26 44.98 14.88
                   
Market Cap (08/23/23) 427.51 497.86 282.59 259.89 206.98 128.85 137.69 96.22 89.97 90.35
price to 2023 sales 4.27 14.80 4.77 4.86 3.14 2.87 5.08 3.58 7.05 9.15
price to ltm earnings 32.75 76.62 90.69 29.90 9.62 16.15 17.26 17.68 20.93 26.85
price to 2023 eps 15.31 56.18 36.85 13.30 11.11 8.29 14.10 11.62 20.12 23.83
market cap to ltm ocf 22.41 81.26 56.04 10.18 14.22 10.87 12.75 10.12 18.99 22.21
market cap to ocf [2x*h1] 28.73 105.37 28.02 12.36 25872.79 13.26 13.31 11.79 18.82 22.21
                   
Enterprise Value 448.96 461.33 324.06 290.06 269.63 162.90 146.05 115.57 78.05 80.68
ev to 2023 sales 4.48 13.71 5.47 5.43 4.08 3.62 5.39 4.30 6.11 8.17

* Merck's significant increase in 2023-H1 RnD expenses was primarily due to a $10.2 billion charge for the acquisition of Prometheus

** Adjusted net income are non-GAAP numbers reported by the company in 8-K filings